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Emily Wright noticed: "Hydrochlorothiazide in pregnancy, thiazide diuretics may cause an increased risk of congenital defects. Take Hydrochlorothiazide as directed, with meals, early in the day to avoid nocturia. Hydrochlorothiazide increases the removal of salts from the blood, it also causes more water to be drawn out of the blood and into the urine. Lab tests, including kidney function, blood pressure, and electrolyte levels, may be performed while you use Hydrochlorothiazide. If you are also taking Hydrochlorothiazide along with diazoxide or a beta-blocker medicine. The kidney to reduce sodium reabsorption in the distal convoluted tubule. The day to avoid nocturia."