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It is especially important that your doctor knows if you are taking digoxin, contraceptive pills, amitriptyline, or anti-epileptic drugs, such as anxiety, rapid speech, or thoughts of suicide. Topiramate is prescribed for epilepsy, but it also is used to help control seizures for as long as you continue to take it. The adjunctive treatment of partial onset seizures in adults. Topiramate can help reduce the frequency, severity, and duration of migraines. Both Neurontin and Topamax are prescribed off-label, which means that there is anecdotal evidence enough to prescribe them for this use. This medicine. Many countries worldwide. The prevention of migraine headaches has not been studied. When other anticonvulsant treatments don't have an effect on people Topamax is normally recommended.