Spironolactone may enhance the blood pressure lowering effect of medicines used to treat high blood pressure. You may prefer to take this medicine in the morning with breakfast or twice a day with breakfast and lunch. It is involved in controlling the balance of salt and water in the body called Aldosterone. There are many conditions that can lead to an accumulation of fluid in the body. Aldactone controls high blood pressure but does not cure it. Aldactone controls high blood pressure.
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