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Prednisolone is commonly used for several days before the needed effect is achieved. Prednisone is inactive in the body and, in order to be effective, first must be converted to Prednisolone by enzymes in the liver. Prednisolone is a synthetic corticosteroid which is often simply called steroid, but it should be noted that it is very different from another group of steroids, called anabolic steroids, which have gained notoriety because of their abuse by some athletes and body builders. Deltasone use is likely to change liver enzyme blood testing and interfere with testing for thyroid diseases. Corticosteroids become exaggerated and may be observed as side effects of this medicine. Corticosteroid. Deltasone is used in much higher doses than the levels of corticosteroids produced naturally by the body. A day or a day and a half.